Claim this global strategic report to understand unique product opportunities by stem cell type, derive more revenue from products sold to stem cell scientists, and identify new product development opportunities before the competition. Use the “Survey of Stem Cell Scientists” to understand technical requirements, unmet needs, and purchasing preferences of stem cell researchers worldwide.
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This report explores unique market opportunities by stem cell type, including mesenchymal stem cells, hematopoietic stem cells, induced pluripotent stem cells, embryonic stem cells, neural stem cells, and more.
The Market for Stem Cell Research Products
Stem cells are primitive cells found in all multi-cellular organisms that are characterized by self-renewal and the capacity to differentiate into any mature cell type. Several broad categories of stem cells exist, including:
Embryonic stem cells, derived from blastocysts
Perinatal stem cells, obtained during the period immediately before and after birth
Adult stem cells, found in adult tissues
Induced pluripotent stem cells, produced by genetically reprogramming adults cells
Cancer stem cells, which give rise to clonal populations of cells that form tumors or disperse in the body
Stem cell research and experimentation have been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types.
In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem and progenitor cells act as a repair system for the body, replenishing specialized cells.
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Traditionally, scientists have worked with both embryonic and adult stem cells as research tools. While the appeal of embryonic cells has been their ability to differentiate into any type of cell, there has been significant ethical, moral and spiritual controversy surrounding their use for research purposes. Although some adult stem cells do have differentiation capacity, it is often limited in nature, which results in fewer options for use.
Thus, when induced pluripotent stem cells (iPSCs) were produced from mouse cells in 2006 by Shinya Yamanaka of Kyoto University in Japan, they represented a promising combination of adult and embryonic stem cell characteristics. By 2007, a series of follow-up experiments were done at Kyoto University in which human adult cells were transformed into iPSC cells. Nearly simultaneously, a research group led by James Thomson at the University of Wisconsin-Madison accomplished the same feat of deriving iPSC lines from human somatic cells.
The possibilities arising from these characteristics have resulted in great commercial interest, with potential applications ranging from the use of stem cells in reversal and treatment of disease, to targeted cell therapy, tissue regeneration, pharmacological testing on cell-specific tissues, and more. Huntington’s disease, Parkinson’s disease, and spinal cord injuries are examples of conditions for which clinical applications involving stem cells could offer benefits in halting or even reversing adverse effects.
Also of interest to clinical researchers is the potential to use stem cells in regenerative medicine. Additionally, the ability to use stem cells to improve drug target validation and toxicology screening is of intense interest to the pharmaceutical industry.
At this time, the following account for the majority of stem cell research:
Basic Research – Understanding stem cell mechanisms and behavior
Regenerative Medicine – Reversal of injury or disease
Drug Target Validation and Drug Delivery – Treatment of disease
Toxicology Screening – Drug safety and efficacy assessment
To facilitate research resulting from interest in these potential far-ranging applications, a large and growing stem cells research products market has emerged.
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While several of these dominant market players have utilized acquisition strategies to grow and capture market share, Merck KGaA has had a particularly strong commitment to this approach, acquiring several other massive major players within the stem cell research products marketplace, including Milllipore on February 26, 2010, for $7.2 billion, and Sigma-Aldrich on September 22, 2014, for $17 billion. Dozens of mid-sized suppliers of stem cell research products also exist, as well as over 100 small specialty providers.
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